Searchable abstracts of presentations at key conferences in endocrinology

ea0016p533 | Obesity | ECE2008

Pentraxin 3 production in human visceral adipose tissue is associated with cardiovascular risk factors

Alberti Luisella , Gilardini Luisa , Girola Andrea , Micheletto Giancarlo , Peri Giuseppe , Doni Andrea , Mantovani Alberto , Invitti Cecilia

Pentraxin 3 (PTX3) is an acute phase protein expressed in the advanced atherosclerotic lesions and produced by endothelial cells, macrophages and, in rodents also by adipocytes under tumour necrosis factor α (TNFα) exposure. We investigated if PTX3 is expressed in human adipose tissue and is associated with cardiometabolic risk factors.Methods: Samples of subcutaneous (SAT) and omental visceral (VAT) adipose tissue were obtained from 21 obese (...